Fig. 1 · Structure
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hTYR/AbTYR-IN-1
hTYR/AbTYR Inhibitor
hTYR/AbTYR-IN-1 is a dual inhibitor targeting human tyrosinase (hTYR) and AbTYR, displaying IC50 values of 5.4 μM and 3.52 μM for each enzyme, respectively. This compound is valuable for studying melanin biosynthesis and enzymatic regulation in melanogenesis-related research. Its inhibition of both hTYR and AbTYR provides a useful tool for investigating therapeutic strategies in conditions involving pigmentation disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1625821-37-5 |
| Applications | hTYR/AbTYR Inhibitor |
| Formula | C18H20N2O3 |
| Molecular Weight | 312.36 |
| SMILES | COC1=CC=CC=C1C(N2CCN(C3=CC=C(O)C=C3)CC2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.