Fig. 1 · Structure

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HV1-IN-1 hydrochloride

hHV1 Inhibitor

HV1-IN-1 hydrochloride is a selective inhibitor of the human voltage-gated proton channel (hHV1), functioning by binding to the voltage-sensing domain (VSD) of the channel. This interaction prevents the channel from opening in response to membrane potential changes. It is employed in research to investigate mechanisms underlying cancer, neuroinflammation, and immune responses, making it a valuable tool for understanding hHV1's role in these biological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1609461-57-5
Applications hHV1 Inhibitor
Formula C19H15ClF3N5O2
Molecular Weight 437.80
SMILES
NC1=NC=C(N1)C2=CC=CC(NC(C3=CC4=C(C=CC(OC(F)(F)F)=C4)N3)=O)=C2.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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