Fig. 1 · Structure
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HV1-IN-2
HV1 Inhibitor
HV1-IN-2 is a selective inhibitor of the human voltage-gated proton channel (HV1), demonstrating an IC50 value of 2.14 μM. This compound exhibits notable anticancer properties, particularly effective in reducing proliferation of THP-1 and MCF-7 cancer cell lines. HV1-IN-2 is a valuable tool for research applications focused on colorectal tumors, leukemia, and breast cancer.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3097367-11-5 |
| Applications | HV1 Inhibitor |
| Formula | C17H14F3N3O |
| Molecular Weight | 333.31 |
| SMILES | NC1=NC=C(C2=CC=C(OCC3=CC=CC(C(F)(F)F)=C3)C=C2)N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.