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Hydrazinocurcumin

Angiogenesis Inhibitor

Hydrazinocurcumin acts as a potent angiogenesis inhibitor by targeting endothelial cell proliferation with an IC50 of 520 nM. This compound disrupts critical angiogenic signaling pathways, inhibiting both endothelial cell migration and tube formation. Hydrazinocurcumin is valuable for research focused on tumor angiogenesis inhibition, metastatic cancer, and various vascular-dependent diseases, including retinopathies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	131068-23-0
Applications	Angiogenesis Inhibitor
Formula	C₂₁H₂₀N₂O₄
Molecular Weight	364.39
Synonyms	Curcumin pyrazole
SMILES	OC1=CC=C(/C=C/C2=NNC(/C=C/C3=CC=C(O)C(OC)=C3)=C2)C=C1OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.