Fig. 1 · Structure
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Hydrochlorothiazide-13C6
Stable Isotope
Hydrochlorothiazide-13C6 is a stable isotope-labeled form of Hydrochlorothiazide (HCTZ), a thiazide diuretic that primarily targets the TGF-β/Smad signaling pathway. It exhibits direct vascular relaxant properties through the activation of calcium-activated potassium (KCA) channels. Hydrochlorothiazide-13C6 is utilized in various research applications, including studies on cardiac function improvement, fibrosis reduction, and antihypertensive effects in cardiovascular research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1261396-79-5 |
| Applications | Stable Isotope |
| Formula | C13C6H8ClN3O4S2 |
| Molecular Weight | 303.70 |
| Synonyms | HCTZ-13C6 |
| SMILES | O=S1([13C]2=[13CH][13C](S(N)(=O)=O)=[13C](Cl)[13CH]=[13C]2NCN1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.