Fig. 1 · Structure
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Hydrocortisone phosphate
Glucocorticoid Derivative
Hydrocortisone phosphate is a glucocorticoid derivative that acts as a substrate for alkaline phosphatase, facilitating the hydrolysis of steroid phosphates. It has been shown to enhance serum luteinizing hormone (LH) levels and increase the activity of magnesium-dependent polymerases within the nucleolus. This compound is valuable for research applications focused on steroid metabolism and hormonal regulation in various biological tissues. Its role in phosphatase activity has been validated in adult mouse tissues, providing insight into enzymatic processes involved in steroid signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 3863-59-0 |
| Applications | Glucocorticoid Derivative |
| Formula | C21H31O8P |
| Molecular Weight | 442.44 |
| Synonyms | Hydrocortisone 21-phosphate; Cortisol 21-phosphate |
| SMILES | C[C@@]12[C@](C(COP(O)(O)=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.