Fig. 1 · Structure

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Hydrocotarnine

Cbl Inhibitor

Hydrocotarnine is a selective Cbl inhibitor that promotes inflammasome-mediated IL-18 secretion, demonstrating potential in the study of inflammatory bowel disease, particularly colitis. Additionally, it enhances GLUT1 expression and augments glucose uptake, suggesting a role in regulating glycolytic metabolism. Furthermore, hydrocotarnine exhibits analgesic effects, making it a valuable compound for cancer research applications focused on pain management.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 550-10-7
Applications Cbl Inhibitor
Formula C12H15NO3
Molecular Weight 221.25
SMILES
CN1CCC2=CC3=C(C(=C2C1)OC)OCO3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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