Hydrodolasetron

Catalog No.: A29339
5-HT(3A)R Blocker
Hydrodolasetron is a potent 5-HT(3A) receptor antagonist, exhibiting an IC50 of 0.29 nM. It is recognized for its antiemetic properties and is a metabolite of Dolasetron, demonstrating enhanced efficacy in blocking nicotinic acetylcholine receptors compared to its parent compound. This compound is valuable in research focused on gastrointestinal disorders and the modulation of serotonin-mediated pathways.
Grouped product items
Size Price Stock Qty
5mg
$345.00
In stock
25mg
$1,530.00
In stock
50mg
$1,950.00
In stock
100mg
$2,480.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHydrodolasetron is a potent 5-HT(3A) receptor antagonist, exhibiting an IC50 of 0.29 nM. It is recognized for its antiemetic properties and is a metabolite of Dolasetron, demonstrating enhanced efficacy in blocking nicotinic acetylcholine receptors compared to its parent compound. This compound is valuable in research focused on gastrointestinal disorders and the modulation of serotonin-mediated pathways.
Product Information
Catalog NumA29339
FormulaC19H22N2O3
Molecular Weight326.39
CAS Number127951-99-9
SMILESO=C(C1=CNC2=C1C=CC=C2)OC3CC4N5CC(O)C(C4)CC5C3
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