Hydrouracil-4-benzazimide-7-NH2 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be conjugated to a target protein ligand using a linker, enabling the construction of proteolysis targeting chimeras (PROTACs). It is of particular interest in pharmacological research for its potential to modulate protein degradation pathways.
Hydrouracil-4-benzazimide-7-NH2 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be conjugated to a target protein ligand using a linker, enabling the construction of proteolysis targeting chimeras (PROTACs). It is of particular interest in pharmacological research for its potential to modulate protein degradation pathways.
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