Hydrouracil-(4-Chlorophenoxy)-O-C-COOH is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound is instrumental in the development of proteolysis-targeting chimeras (PROTACs) by linking to target protein ligands through a suitable linker. Its utility in research applications includes studies on targeted protein degradation and modulation of cellular pathways via ubiquitin-proteasome system engagement.
Hydrouracil-(4-Chlorophenoxy)-O-C-COOH is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound is instrumental in the development of proteolysis-targeting chimeras (PROTACs) by linking to target protein ligands through a suitable linker. Its utility in research applications includes studies on targeted protein degradation and modulation of cellular pathways via ubiquitin-proteasome system engagement.
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