Fig. 1 · Structure
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Hydroxyacetone
F-actin Modulator
Hydroxyacetone primarily targets F-actin and functions as a modulator of its stability. This compound has been shown to induce mitochondrial stress and increase reactive oxygen species (ROS) levels in cells, particularly in BEAS-2B airway epithelial cells, where it reduces mitochondrial reductase activity with an IC50 of 5.53 mg/mL. Hydroxyacetone promotes cellular effects such as rounding and the formation of apoptotic bodies at elevated concentrations, highlighting its biological activity and potential applications in research focused on oxidative damage and respiratory toxicity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 116-09-6 |
| Applications | F-actin Modulator |
| Formula | C3H6O2 |
| Molecular Weight | 74.08 |
| SMILES | CC(CO)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.