Fig. 1 · Structure
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(-)-Hydroxycitric acid lactone
ATP-citrate Lyase Inhibitor
(-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase, an enzyme that catalyzes the extramitochondrial cleavage of citrate into oxaloacetate and acetyl-CoA. By inhibiting this enzyme, (-)-Hydroxycitric acid lactone reduces the availability of acetyl-CoA, thereby limiting fatty acid synthesis. This compound is utilized in obesity research and has potential applications in weight management studies, making it a valuable tool for investigating metabolic pathways related to energy balance and lipid metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 27750-13-6 |
| Applications | ATP-citrate Lyase Inhibitor |
| Formula | C6H6O7 |
| Molecular Weight | 190.11 |
| Synonyms | Garcinia lactone |
| SMILES | O[C@](CC(O1)=O)(C(O)=O)[C@H]1C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.