Fig. 1 · Structure

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Hydroxyrubicin

Antitumor Agents

Hydroxyrubicin is an antitumor agent that primarily targets topoisomerase II, facilitating DNA cleavage and unwinding. This compound demonstrates significant inhibitory activity against tumor cells, making it a valuable tool in cancer research. Hydroxyrubicin is particularly useful for investigating multidrug-resistant (MDR) leukemia, providing insights into resistance mechanisms and potential therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 73113-90-3
Applications Antitumor Agents
Formula C27H28O12
Molecular Weight 544.50
SMILES
OC1=C2C([C@H](C[C@@](C(CO)=O)(O)C2)O[C@@]3([H])C[C@@H]([C@H](O)[C@H](C)O3)O)=C(O)C4=C1C(C5=CC=CC(OC)=C5C4=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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