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Hydroxysaikosaponin D

Catalog No.: A96563
Hepatocytoprotective Saponin
Hydroxysaikosaponin D is a hepatocytoprotective saponin derived from the roots of Bupleurum scorzonerifolium WILLD. It exhibits efficacy in inhibiting D-galactosamine-induced cytotoxicity in primary cultured rat hepatocytes and demonstrates protective effects against D-galactosamine/LPS-induced liver injury in murine models. This compound is valuable for research focused on liver injury mechanisms and potential therapeutic interventions.
Hydroxysaikosaponin D 173559-75-6 Hepatocytoprotective Saponin
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHydroxysaikosaponin D is a hepatocytoprotective saponin derived from the roots of Bupleurum scorzonerifolium WILLD. It exhibits efficacy in inhibiting D-galactosamine-induced cytotoxicity in primary cultured rat hepatocytes and demonstrates protective effects against D-galactosamine/LPS-induced liver injury in murine models. This compound is valuable for research focused on liver injury mechanisms and potential therapeutic interventions.
Product Information
Catalog NumA96563
FormulaC42H70O14
Molecular Weight799.00
CAS Number173559-75-6
SMILESC[C@]12[C@]3(C([C@@]4([H])[C@@]([C@@H](C3)O)(CCC(C)(C4)C)CO)=C[C@H]([C@]1([H])[C@@]5([C@@]([C@@](C)([C@H](CC5)O[C@H]6[C@@H]([C@H]([C@H]([C@H](O6)C)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO)O)CO)([H])CC2)C)O)C
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