Fig. 1 · Structure
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Hydroxytanshinone IIA
Tanshinone IIA Metabolite
Hydroxytanshinone IIA is a hydroxylated metabolite of Tanshinone IIA, acting primarily through inhibition of angiogenesis. This compound targets the protein kinase domains of the vascular endothelial growth factor (VEGF) and its receptor VEGFR2, thereby modulating vascular processes. Hydroxytanshinone IIA is utilized in research focused on cancer biology, cardiovascular diseases, and therapeutic angiogenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 18887-18-8 |
| Applications | Tanshinone IIA Metabolite |
| Formula | C19H18O4 |
| Molecular Weight | 310.34 |
| SMILES | O=C(C1=C2C=CC3=C1C(O)CCC3(C)C)C(C4=C2OC=C4C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.