Fig. 1 · Structure

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Hydroxyzine-d8 dihydrochloride

Stable Isotope

Hydroxyzine-d8 dihydrochloride is a deuterium-labeled derivative of hydroxyzine, a benzodiazepine antihistamine. It functions as an oral histamine H1-receptor and serotonin antagonist, exhibiting anxiolytic properties. This compound is valuable for research applications focused on generalized anxiety disorder and other related disorders, enabling the study of histaminergic and serotonergic systems in anxiety modulation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1808202-93-8
Applications Stable Isotope
Formula C21H21D8Cl3N2O2
Molecular Weight 455.88
SMILES
OCCOCCN(C([2H])([2H])C1([2H])[2H])C([2H])([2H])C([2H])([2H])N1C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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