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Hyocholic acid

Catalog No.: A60386
Anti-diabete Agent
Hyocholic acid is a bile acid primarily found in porcine sources, demonstrating significant anti-diabetic properties. Its mechanism involves promoting GLP-1 secretion through activation of TGR5 and inhibition of FXR in enteroendocrine cells. This compound has potential applications in research aimed at understanding and treating type 2 diabetes and related metabolic disorders.
Hyocholic acid 547-75-1 Anti-diabete Agent
Grouped product items
Size Price Stock Qty
1mg
$35.00
In stock
5mg
$80.00
In stock
10mg
$150.00
In stock
25mg
$335.00
In stock
50mg
$485.00
In stock
100mg
$675.00
In stock
500mg
$1,350.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHyocholic acid is a bile acid primarily found in porcine sources, demonstrating significant anti-diabetic properties. Its mechanism involves promoting GLP-1 secretion through activation of TGR5 and inhibition of FXR in enteroendocrine cells. This compound has potential applications in research aimed at understanding and treating type 2 diabetes and related metabolic disorders.
Product Information
Catalog NumA60386
FormulaC24H40O5
Molecular Weight408.57
CAS Number547-75-1
SMILESC[C@@H]([C@]1(CC[C@]2([C@@]3([C@@H]([C@@H]([C@@]4(C[C@@H](CC[C@@]4([C@]3(CC[C@@]21C)[H])C)O)[H])O)O)[H])[H])[H])CCC(O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

GPCR/G Protein > GLP-1 receptors