Fig. 1 · Structure
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Hyocholic acid
Anti-diabete Agent
Hyocholic acid is a bile acid primarily found in porcine sources, demonstrating significant anti-diabetic properties. Its mechanism involves promoting GLP-1 secretion through activation of TGR5 and inhibition of FXR in enteroendocrine cells. This compound has potential applications in research aimed at understanding and treating type 2 diabetes and related metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 547-75-1 |
| Applications | Anti-diabete Agent |
| Formula | C24H40O5 |
| Molecular Weight | 408.57 |
| SMILES | C[C@@H]([C@]1(CC[C@]2([C@@]3([C@@H]([C@@H]([C@@]4(C[C@@H](CC[C@@]4([C@]3(CC[C@@]21C)[H])C)O)[H])O)O)[H])[H])[H])CCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.