Fig. 1 · Structure
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Hypoxystat
Hypoxia Mimetic
Hypoxystat is an orally active hypoxia mimetic that enhances hemoglobin's oxygen affinity, thereby limiting oxygen release to tissues and inducing localized hypoxia. Its biological activities include a reduction in Iba1+ cells and the ability to cause systemic hypoxia. Hypoxystat has demonstrated efficacy in addressing hyperglycemia in mouse models of both type 1 and type 2 diabetes. Additionally, it extends lifespan and mitigates neuropathological and behavioral deficits in a prominent mouse model of Leigh syndrome, making it a valuable tool for research in metabolic disorders and neurodegenerative diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2414508-40-8 |
| Applications | Hypoxia Mimetic |
| Formula | C21H21NO5 |
| Molecular Weight | 367.40 |
| SMILES | O=C(N1CCCC[C@H]1COC2=CC=CC(O)=C2C=O)C3=C(C=O)C=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.