Fig. 1 · Structure

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IAJD249

Ionizable Lipid

IAJD249 is an ionizable lipid known for its capacity to form unstable non-bilayer structures in acidic conditions, facilitating endosomal escape and efficient cytosolic delivery of RNA. This property makes IAJD249 a valuable component in the formulation of liposomes, enhancing the delivery efficiency of nucleic acid therapeutics. Its application is particularly relevant in RNA-based research and therapeutic development.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3076338-32-1
Applications Ionizable Lipid
Formula C39H78N2O6
Molecular Weight 671.05
SMILES
O=C(CCCN1CCN(CC1)CCO)OCC(COCCCCCCCC)(COCCCCCCCC)COCCCCCCCC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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