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IAM1363

HER2 Inhibitor

IAM1363 is a selective, irreversible inhibitor targeting the human epidermal growth factor receptor 2 (HER2). It demonstrates greater than 1,000-fold selectivity for HER2 over the epidermal growth factor receptor (EGFR), making it a valuable tool for investigating advanced HER2-positive cancers. This compound is particularly relevant for research on HER2-driven non-small cell lung cancer (NSCLC), facilitating the exploration of novel therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3031413-24-5
Applications	HER2 Inhibitor
Formula	C₃₀H₃₃N₉O₂
Molecular Weight	551.66
SMILES	N(C=1C2=C(C=CN2N=CN1)C3CCN(C(/C=C/CN(C)C)=O)CC3)C4=CC(C)=C(OC5=CC=6N(C=C5)N=CN6)C=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.