Fig. 1 · Structure
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IAMA-6
NKCC1 Inhibitor
IAMA-6 is a selective inhibitor of the Na+/K+/2Cl- cotransporter NKCC1, exhibiting neuroprotective properties. This reagent is valuable for investigating various neurological disorders, including drug-resistant epilepsy, such as temporal lobe epilepsy and Dravet syndrome, as well as autism spectrum disorders and Down syndrome. Its ability to selectively modulate NKCC1 activity makes it a potent tool for research in neurobiology and related therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2497525-96-7 |
| Applications | NKCC1 Inhibitor |
| Formula | C17H25F3N2O4S |
| Molecular Weight | 410.45 |
| SMILES | CN(S(=O)(C1=CC(C(O)=O)=CC=C1NCCCCCCCC(F)(F)F)=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.