Ibudilast-d7

Catalog No.: A42064
Stable Isotope
Ibudilast-d7 is a deuterium-labeled derivative of Ibudilast, a selective phosphodiesterase (PDE) inhibitor that modulates cyclic AMP levels. This compound exhibits notable platelet anti-aggregatory effects and is relevant in asthma research due to its inhibitory impact on tracheal smooth muscle contractility. Furthermore, Ibudilast is investigated for its potential neuroprotective and anti-dementia properties, particularly in countering neurotoxicity associated with activated microglia.
Grouped product items
Size Price Stock Qty
1mg
$630.00
In stock
Bulk Size
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIbudilast-d7 is a deuterium-labeled derivative of Ibudilast, a selective phosphodiesterase (PDE) inhibitor that modulates cyclic AMP levels. This compound exhibits notable platelet anti-aggregatory effects and is relevant in asthma research due to its inhibitory impact on tracheal smooth muscle contractility. Furthermore, Ibudilast is investigated for its potential neuroprotective and anti-dementia properties, particularly in countering neurotoxicity associated with activated microglia.
Product Information
Catalog NumA42064
FormulaC14H11D7N2O
Molecular Weight237.35
CAS Number2713301-45-0
SMILESO=C(C1=C2C=CC=CN2N=C1C(C)C)C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H]
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