Fig. 1 · Structure
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ICAM-1-IN-1
ICAM-1/E-selectin Inhibitor
ICAM-1-IN-1 is a potent and selective inhibitor of ICAM-1 and E-selectin, exhibiting IC50 values of 5 nM and 7 nM, respectively. This compound is essential for studying leukocyte adhesion and migration processes, particularly in inflammation and immune response research. Its specificity allows for detailed investigations into the role of ICAM-1 and E-selectin in various pathological conditions, making it a valuable tool for therapeutic exploration.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 251994-14-6 |
| Applications | ICAM-1/E-selectin Inhibitor |
| Formula | C15H11BrN2O2S |
| Molecular Weight | 363.23 |
| SMILES | O=C(C(S1)=CC2=C1C=NC=C2OC3=CC=C(Br)C=C3)NC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.