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ICAM-1988

LFA-1 Antagonist

ICAM-1988 is a small molecule antagonist of lymphocyte function-associated antigen-1 (LFA-1) that effectively disrupts the interaction between LFA-1 and intercellular adhesion molecule-1 (ICAM-1). This disruption has been shown to exert anti-inflammatory effects, making ICAM-1988 a valuable tool in the study of immune responses and inflammatory diseases. Its research applications may include investigations into immune cell adhesion and migration, as well as the modulation of inflammatory pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	444169-80-6
Applications	LFA-1 Antagonist
Formula	C₂₂H₂₂Cl₂N₄O₆S
Molecular Weight	541.40
SMILES	O=C([C@@H](NC(C1=C(C=C(C=C1Cl)CNC(/C=C/C2=CC=CO2)=O)Cl)=O)CNC([C@H]3NCSC3)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.