Fig. 1 · Structure
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ICI 162846
H2 Receptor Antagonist
ICI 162846 is a potent orally active antagonist of the H2 receptor, primarily involved in the regulation of gastric acid secretion. It effectively inhibits acid production and has been shown to enhance histamine secretion in chronic duodenal ulcer models. This compound is utilized in research focused on gastrointestinal disorders, particularly in studies aimed at preventing chronic duodenal ulcers.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 84545-30-2 |
| Applications | H2 Receptor Antagonist |
| Formula | C11H17F3N6O |
| Molecular Weight | 306.29 |
| SMILES | O=C(N)CCCCN1N=C(NC(NCC(F)(F)F)=N)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.