Fig. 1 · Structure
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ICI-199441 hydrochloride
κ-Opioid Receptor Agonist
ICI-199441 hydrochloride is a potent and selective κ-opioid receptor agonist that exhibits significant analgesic properties. This compound has been shown to enhance cardiac resistance to ischemia/reperfusion injury, making it valuable in studies related to cardiovascular protection and pain management. Its specific targeting of the κ-opioid receptor underscores its potential utility in research applications focusing on the modulation of pain pathways and ischemic heart conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 115199-84-3 |
| Applications | κ-Opioid Receptor Agonist |
| Formula | C21H25Cl3N2O |
| Molecular Weight | 427.80 |
| SMILES | O=C(N(C)[C@@H](C1=CC=CC=C1)CN2CCCC2)CC3=CC=C(Cl)C(Cl)=C3.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.