Fig. 1 · Structure
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ICL-SIRT078
Drug Derivative
ICL-SIRT078 is a drug derivative that acts as a potent inhibitor of sirtuin enzymes, specifically SIRT1 and SIRT2. This compound demonstrates significant potential in modulating cellular metabolism and influencing gene expression through epigenetic mechanisms. ICL-SIRT078 is suitable for applications in studies related to aging, cancer, and metabolic disorders, providing researchers a valuable tool for understanding the role of sirtuins in various biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1060430-64-9 |
| Applications | Drug Derivative |
| Formula | C28H26N4O2S |
| Molecular Weight | 482.60 |
| SMILES | O=C1C2=C(SC3=C2CCC(C3)NCC4=CC=CN=C4)N=CN1CC5=C(C=CC6=C5C=CC=C6)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.