ICMT-IN-3

Catalog No.: A60957
ICMT Inhibitor
ICMT-IN-3 is a potent inhibitor of Isoprenylcysteine Carboxyl Methyltransferase (ICMT) with an IC50 value of 0.015 μM. This compound is crucial for studying protein modification processes, particularly in the context of signal transduction and cellular regulation. It serves as a valuable tool for investigating the role of ICMT in various biological pathways and its potential implications in disease mechanisms.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionICMT-IN-3 is a potent inhibitor of Isoprenylcysteine Carboxyl Methyltransferase (ICMT) with an IC50 value of 0.015 μM. This compound is crucial for studying protein modification processes, particularly in the context of signal transduction and cellular regulation. It serves as a valuable tool for investigating the role of ICMT in various biological pathways and its potential implications in disease mechanisms.
Product Information
Catalog NumA60957
FormulaC22H29NO2
Molecular Weight339.47
CAS Number1313602-73-1
SMILESCOC1=CC(NCCC2(C3=CC=CC=C3)CC(C)(C)OCC2)=CC=C1
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