ICMT-IN-42

Catalog No.: A60955
ICMT Inhibitor
ICMT-IN-42 is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), demonstrating an IC50 value of 0.054 μM. This compound is valuable for research into the role of ICMT in post-translational modifications and protein function regulation. It is suitable for studies investigating cancer biology, signal transduction, and therapeutic development targeting ICMT pathways.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionICMT-IN-42 is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), demonstrating an IC50 value of 0.054 μM. This compound is valuable for research into the role of ICMT in post-translational modifications and protein function regulation. It is suitable for studies investigating cancer biology, signal transduction, and therapeutic development targeting ICMT pathways.
Product Information
Catalog NumA60955
FormulaC23H31NO
Molecular Weight337.50
CAS Number1313602-67-3
SMILESCC1=CC(C)=CC(NCCC2(C3=CC=CC=C3)CC(C)(C)OCC2)=C1
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