Fig. 1 · Structure

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ICMT-IN-55

ICMT Inhibitor

ICMT-IN-55 is a selective inhibitor of isoprenylcysteine carboxymethyltransferase (ICMT) with an IC50 of 90 nM. This compound plays a crucial role in inhibiting ICMT activity, leading to the disruption of protein processing involved in various cellular signaling pathways. ICMT-IN-55 is utilized in research focused on understanding the biological significance of protein lipidation and its implications in cancer and other diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1313602-77-5
Applications ICMT Inhibitor
Formula C22H26F3NO2
Molecular Weight 393.44
SMILES
CC1(C)CC(CCNC2=CC=CC(OC(F)(F)F)=C2)(C3=CC=CC=C3)CCO1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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