Fig. 1 · Structure
Documents & Downloads
ICOS-IN-1
ICOS/ICOS-L Interaction Inhibitor
ICOS-IN-1 is a selective inhibitor of the interaction between Inducible T-cell Co-stimulator (ICOS) and its ligand (ICOS-L), with an IC50 value of 29.38 μM. This compound plays a critical role in modulating immune checkpoints and demonstrates significant potential in immunological research. ICOS-IN-1 can be utilized in studies aimed at understanding T cell activation and regulation, potentially aiding in the development of novel therapeutics for immune-related diseases.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1006002-58-9 |
| Applications | ICOS/ICOS-L Interaction Inhibitor |
| Formula | C17H14Cl2N2O2 |
| Molecular Weight | 349.21 |
| SMILES | OC1=C(C2=NNC=C2)C=CC(OCC3=CC=C(Cl)C(Cl)=C3)=C1C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.