Fig. 1 · Structure
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iCRT-5
CRT Inhibitor
iCRT-5 is a β-catenin-regulated transcription (CRT) inhibitor that specifically targets the Wnt/β-catenin signaling pathway. It effectively blocks Wnt/β-catenin reporter activity and downregulates β-catenin expression. This reagent is utilized in various research applications, particularly in studies related to multiple myeloma and the modulation of cellular processes influenced by β-catenin signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 18623-44-4 |
| Applications | CRT Inhibitor |
| Formula | C16H17NO5S2 |
| Molecular Weight | 367.44 |
| SMILES | O=C(O)CCCN(C/1=O)C(SC1=C/C2=CC=C(OC)C(OC)=C2)=S |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.