Fig. 1 · Structure
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ICy-Q
Anticancer Agent
ICy-Q is a near-infrared (NIR) reagent that targets quinone oxidoreductase 1 (NQO-1), facilitating the release of the reduction product ICy-OH upon activation. ICy-OH selectively induces cell death in pancreatic cancer via the pyroptosis pathway, demonstrating significant therapeutic potential in oncology. This compound serves as a valuable tool for quick and precise diagnosis of intraoperative pathological specimens, enhancing the efficacy of cancer treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2863682-83-9 |
| Applications | Anticancer Agent |
| Formula | C48H50I2N2O5 |
| Molecular Weight | 988.73 |
| SMILES | CC1=C(C(C(C(C)(C)CC(N(C2=CC=C(C=C2)COC3=CC4=C(C=C5CCCC(/C=C/C6=[N+](C7=C(C6(C)C)C=C(C=C7)I)C)=C5O4)C=C3)C)=O)=C(C1=O)C)=O)C.[I-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.