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Idarubicin HCl

Topoisomerase inhibitor

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Catalog No. A10465

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Idarubicin HCl 5mg A10465-5
Idarubicin HCl 10mg A10465-10
Idarubicin HCl 50mg A10465-50
Idarubicin HCl 100mg A10465-100
Idarubicin HCl 10mM * 1mL in DMSO A10465-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Idarubicin is an anthracycline antibiotic that is an anti-leukemia agent with higher DNA binding capacity and greater cytotoxicity than daunorubicin.

Idarubicin HCl

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Publications citing Adooq Products
Idarubicin HCl Citations (1)
  • Wei Y, .et al. SUMO-Targeted DNA Translocase Rrp2 Protects the Genome from Top2-Induced DNA Damage, Mol Cell, 2017, Jun 1;66(5):581-596.e6 PMID: 28552615

Chemical Information

Catalog Num A10465
Actions Inhibitor
M. Wt 534
Formula C26H28ClNO9
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 57852-57-0
Synonyms Idamycin, Zavedos, 4-demethoxydaunorubicin, DMDR, IMI-30
SMILES C[[email protected]]1[[email protected]]([[email protected]](C[[email protected]@H](O1)O[[email protected]]2C[[email protected]@](CC3=C(C4=C(C(=C23)O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O.Cl

Biological Activity

Idarubicin is an anthracycline antibiotic that is an anti-leukemia agent with higher DNA binding capacity and greater cytotoxicity than daunorubicin.
Topo II (MCF-7 cells) (Cell-free assay) Multicellular spheroids (Cell-free assay)
3.3 ng/mL7.9 ng/mL


Solubility (25°C)* In vitro DMSO 100 mg/mL (187.28 mM)
Water 7 mg/mL heating (13.1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.73 mL 93.63 mL 187.27mL
0.5 mM 3.75 mL 18.73 mL 37.45 mL
1 mM 1.87 mL 9.36 mL 18.73 mL
5 mM 0.37 mL 1.87 mL 3.75 mL

*The above data is based on the productmolecular weight 534. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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