Fig. 1 · Structure
Documents & Downloads
Idelalisib-d5
p110δ Inhibitor
Idelalisib-d5 is a deuterated form of Idelalisib, a highly selective inhibitor of the p110δ isoform of PI3-kinase. This compound demonstrates significant antiproliferative activity against various cancer cell lines by disrupting key signaling pathways involved in cell growth and survival. Idelalisib-d5 is primarily used in research exploring the mechanisms of cancer therapy and the role of the PI3K pathway in hematological malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1830330-31-8 |
| Applications | p110δ Inhibitor |
| Formula | C22H13D5FN7O |
| Molecular Weight | 420.45 |
| Synonyms | CAL-101 d5; GS-1101 d5 |
| SMILES | O=C1N(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C([C@@H](NC3=C4N=CNC4=NC=N3)CC)=NC5=C1C(F)=CC=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.