IDH-305

Catalog No.: A16943

IDH1 inhibitor

IDH-305

IDH-305 Chemical Structure

CAS NO. 1628805-46-8

IDH305 is an inhibitor of the citric acid cycle enzyme isocitrate dehydrogenase [NADP] cytoplasmic (isocitrate dehydrogenase 1; IDH1) with mutations at residue R132 (IDH1(R132)), with potential antineoplastic activity.

Availability: In stock

Package Price Qty
2 mg
$130.00
5 mg
$320.00
10 mg
$520.00
50 mg
$1,380.00
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Biological Activity

IDH305 is an inhibitor of the citric acid cycle enzyme isocitrate dehydrogenase [NADP] cytoplasmic (isocitrate dehydrogenase 1; IDH1) with mutations at residue R132 (IDH1(R132)), with potential antineoplastic activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.39 mL 101.95 mL 203.89 mL
0.5 mM 4.08 mL 20.39 mL 40.78 mL
1 mM 2.04 mL 10.19 mL 20.39 mL
5 mM 0.41 mL 2.04 mL 4.08 mL

*The above data is based on the productmolecular weight 490.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16943
Actions Inhibitor
CAS No. 1628805-46-8
Formula C23H22F4N6O2
M. Wt 490.46
Purity >98%
Synonyms IDH305, IDH 305
SMILES O=C1OC[[email protected]]([[email protected]@H](F)C)N1C2=NC(N[[email protected]](C3=CC(C)=C(C4=CC(C(F)(F)F)=NC=C4)C=N3)C)=NC=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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