IDH1 Inhibitor 2
DH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM.
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Adooq's IDH1 Inhibitor 2 has been cited by 1 publications
- Derek Dang, .et al. , Cancer Cell, 2025, Jun 9;43(6):1159-1174 PMID: 40378837
Biological Activity
| Description | DH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM. |
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Product Information
| Catalog Num | A18420 |
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| Formula | C26H22N4O |
| Molecular Weight | 406.48 |
| CAS Number | 2244895-42-7 |
| SMILES | N#CC1=C[C@@]2(C3=CC=CC=C3)[C@](CCC4=C2N=C(NC5=CC=CC=C5)N=C4)([H])[C@H](C)C1=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
