IDH1 Inhibitor 2

Catalog No.: A18420

IDH1 inhibitor

IDH1 Inhibitor 2

IDH1 Inhibitor 2 Chemical Structure

CAS NO. 2244895-42-7

DH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $320.00

Special Price $256.00

5 mg

Regular Price: $960.00

Special Price $768.00

10 mg

Regular Price: $1,600.00

Special Price $1,280.00

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Biological Activity

DH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.6 mL 123.01 mL 246.01 mL
0.5 mM 4.92 mL 24.6 mL 49.2 mL
1 mM 2.46 mL 12.3 mL 24.6 mL
5 mM 0.49 mL 2.46 mL 4.92 mL

*The above data is based on the productmolecular weight 406.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18420
Actions Inhibitor
CAS No. 2244895-42-7
Formula C26H22N4O
M. Wt 406.48
Purity >98%
SMILES N#CC1=C[[email protected]@]2(C3=CC=CC=C3)[[email protected]](CCC4=C2N=C(NC5=CC=CC=C5)N=C4)([H])[[email protected]](C)C1=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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