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IDR-HH2

Catalog No.: A48864
Immunomodulatory Peptide
IDR-HH2 is an immunomodulatory peptide targeting the host cytokine and chemokine milieu. It facilitates the adhesion of monocytes and THP-1 cells to fibronectin, enhancing immune cell recruitment. Additionally, IDR-HH2 exhibits antibacterial properties, demonstrating inhibitory effects against Pseudomonas aeruginosa and Staphylococcus aureus, with minimum inhibitory concentration (MIC) values of 75 µg/mL and 38 µg/mL, respectively. This peptide is valuable for research in immunology and antimicrobial studies.
IDR-HH2 1214699-22-5 Immunomodulatory Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIDR-HH2 is an immunomodulatory peptide targeting the host cytokine and chemokine milieu. It facilitates the adhesion of monocytes and THP-1 cells to fibronectin, enhancing immune cell recruitment. Additionally, IDR-HH2 exhibits antibacterial properties, demonstrating inhibitory effects against Pseudomonas aeruginosa and Staphylococcus aureus, with minimum inhibitory concentration (MIC) values of 75 µg/mL and 38 µg/mL, respectively. This peptide is valuable for research in immunology and antimicrobial studies.
Product Information
Catalog NumA48864
FormulaC62H117N23O13
Molecular Weight1392.74
CAS Number1214699-22-5
SequenceVal-Gln-Leu-Arg-Ile-Arg-Val-Ala-Val-Ile-Arg-Ala-NH2
Sequence shorteningVQLRIRVAVIRA-NH2
SMILES[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)C)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)[C@H](C)C)=O)C)=O)[C@H](C)C)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)(NC([C@@H](NC([C@@H](NC([C@H](C(C)C)N)=O)CCC(N)=O)=O)CC(C)C)=O)CCCNC(=N)N
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