Fig. 1 · Structure
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IDX-320
Pipecolic Acid Derivative
IDX-320 is a pipecolic acid derivative that inhibits the NS3/4a proteases of the hepatitis C virus (HCV) across multiple genotypes, including 1a, 1b, 2a, and 4a, with an IC50 ranging from 0.8 to 1.9 nM. This compound is valuable for studying HCV infection mechanisms and developing antiviral strategies. Its potent inhibitory action makes IDX-320 a useful tool for researchers focusing on hepatitis C virus biology and treatment interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1251165-81-7 |
| Applications | Pipecolic Acid Derivative |
| Formula | C37H43F3N6O7S2 |
| Molecular Weight | 804.90 |
| SMILES | O=C(NS(=O)(C1(CC1)C)=O)[C@]23NC([C@@](C[C@@H](OC4=CC(C5=NC(C(F)(F)F)=CS5)=NC6=C(C)C(OC)=CC=C46)CC7)([H])N7C(N(C)CCCC/C=C\[C@]2([H])C3)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.