Fig. 1 · Structure
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IGP-5
sn-Glycerol 3-phosphate Dehydrogenase Inhibitor
IGP-5 is a selective inhibitor of mitochondrial sn-Glycerol 3-phosphate Dehydrogenase (mGPDH), exhibiting an IC50 of 0.7 μM for H2O2 production inhibition. This compound is valuable for investigating energy metabolism and oxidative stress responses. Its targeted inhibition provides a useful tool for elucidating the role of mGPDH in various metabolic processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 351978-83-1 |
| Applications | sn-Glycerol 3-phosphate Dehydrogenase Inhibitor |
| Formula | C21H17N3O3 |
| Molecular Weight | 359.38 |
| SMILES | O=C(CCC(NC1=CC=C(C2=NC3=CC4=C(C=C3N2)C=CC=C4)C=C1)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.