Fig. 1 · Structure

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IGS-1.76

NCS-1/Ric8a PPI Inhibitor

IGS-1.76 is a potent inhibitor of the human NCS-1/Ric8a protein-protein interaction. It demonstrates a significantly enhanced affinity for human NCS-1, effectively modulating the NCS-1/Ric8a complex. This compound is valuable for studies investigating the roles of NCS-1 and Ric8a in cellular signaling and neurobiology.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 313480-47-6
Applications NCS-1/Ric8a PPI Inhibitor
Formula C22H18N2OS
Molecular Weight 358.46
SMILES
O=C(NC1=NC2=CC=CC=C2S1)CC(C3=CC=CC=C3)C4=CC=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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