IHR-1 is a cell membrane impermeable antagonist of Smoothened (Smo), a key component of the Hedgehog signaling pathway. This compound effectively inhibits Smo activity, making it a valuable tool for studying Hedgehog-related biological processes and disease states, such as cancer and developmental disorders. IHR-1's specificity for Smo allows for targeted research into the mechanistic roles of this pathway in various cellular contexts.
IHR-1 is a cell membrane impermeable antagonist of Smoothened (Smo), a key component of the Hedgehog signaling pathway. This compound effectively inhibits Smo activity, making it a valuable tool for studying Hedgehog-related biological processes and disease states, such as cancer and developmental disorders. IHR-1's specificity for Smo allows for targeted research into the mechanistic roles of this pathway in various cellular contexts.
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