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IIP0943

Name: IIP0943
Brand: Adooq Bioscience
SKU: A56912
Availability: OutOfStock

Cat. No. A56912 CAS 3040106-93-9

PLK1 Inhibitor

IIP0943 is a potent and selective inhibitor of PLK1 (polo-like kinase 1), exhibiting an IC50 of 5.1 nM. This compound demonstrates significant antiproliferative activity against HCT116 cancer cells, with an IC50 of 0.22 µM. IIP0943 is a valuable tool for researchers investigating cancer therapeutics and the role of PLK1 in cell cycle regulation and tumor growth.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3040106-93-9
Applications	PLK1 Inhibitor
Formula	C₂₆H₂₈N₆O₃S
Molecular Weight	504.60
SMILES	CN1CCN(C2=CC(NC3=NC=C(C)C(OC4=CC=CC5=C4SC(C(N)=O)=C5)=N3)=C(OC)C=C2)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.