Fig. 1 · Structure

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IK-862

TACE Inhibitor

IK-862 is a selective inhibitor of Tumor Necrosis Factor-alpha Converting Enzyme (TACE), which plays a critical role in the release of pro-inflammatory cytokines. As a TACE inhibitor, IK-862 exhibits key biological activity by reducing tumor progression and inflammation, making it valuable in cancer and inflammatory disease research. This compound can be utilized in studies focused on understanding the role of TACE in various pathological processes and therapeutic interventions targeting cytokine regulation.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 478911-60-3
Applications TACE Inhibitor
Formula C25H27N3O4
Molecular Weight 433.50
SMILES
C[C@]1(C2=CC=C(C=C2)OCC3=CC(C)=NC4=C3C=CC=C4)C(N(CC1)[C@H](C)C(NO)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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