IKFQFHFD

Catalog No.: A48832
pH-responsive And Self-assembling Peptide
IKFQFHFD is a pH-responsive self-assembling peptide that exhibits biocompatibility at neutral pH. When exposed to acidic conditions, it transforms into an antimicrobial peptide-like structure, demonstrating significant potential in targeting biofilm infections. This peptide can be applied in research focused on chronic wound management, including venous ulcers, diabetic ulcers, and pressure ulcers, offering insights into novel therapeutic strategies.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIKFQFHFD is a pH-responsive self-assembling peptide that exhibits biocompatibility at neutral pH. When exposed to acidic conditions, it transforms into an antimicrobial peptide-like structure, demonstrating significant potential in targeting biofilm infections. This peptide can be applied in research focused on chronic wound management, including venous ulcers, diabetic ulcers, and pressure ulcers, offering insights into novel therapeutic strategies.
Product Information
Catalog NumA48832
FormulaC54H72N12O12
Molecular Weight1081.22
CAS Number2169935-95-7
SequenceIle-Lys-Phe-Gln-Phe-His-Phe-Asp
Sequence shorteningIKFQFHFD
SMILES[C@@H](CC1=CN=CN1)(NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CCCCN)=O)=O)CCC(N)=O)=O)=O)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O
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