Fig. 1 · Structure
Documents & Downloads
Ilepatril
Angiotensin-converting Enzyme (ACE) Inhibitor
Ilepatril is a dual inhibitor of angiotensin-converting enzyme (ACE) and neutral endopeptidase, providing significant therapeutic potential in managing type 2 diabetic nephropathy. In studies using the obese Zucker diabetic fatty (ZDF) rat model, Ilepatril demonstrated a dose-dependent reduction in albuminuria. This compound offers a novel approach that extends beyond traditional metabolic control, targeting the underlying mechanisms of type 2 diabetic nephropathy.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 473289-62-2 |
| Applications | Angiotensin-converting Enzyme (ACE) Inhibitor |
| Formula | C22H28N2O5S |
| Molecular Weight | 432.53 |
| Synonyms | AVE 7688 |
| SMILES | O=C([C@@H]1CCC[C@]2([H])C3=CC=CC=C3C[C@H](NC([C@@H](SC(C)=O)C(C)C)=O)C(N21)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.