Fig. 1 · Structure
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ILK-IN-3
ILK Inhibitor
ILK-IN-3 is a potent orally active inhibitor of integrin-linked kinase (ILK), a crucial regulator of cell signaling pathways associated with tumor progression and survival. This compound enhances the anticancer efficacy of Docetaxel in orthotopic LCC6 tumor models, making it a valuable tool for research in cancer therapeutics. Its ability to modulate ILK activity positions ILK-IN-3 as a significant molecule for studying cancer biology and potential treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 6975-75-3 |
| Applications | ILK Inhibitor |
| Formula | C10H12N6O |
| Molecular Weight | 232.24 |
| SMILES | NC1=NNC(N)=C1/N=N/C2=CC=C(OC)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.