Ilorasertib

Catalog No.: A20982

ATP-competitive multitargeted kinase inhibitor

Ilorasertib

Ilorasertib Chemical Structure

CAS NO. 1227939-82-3

Ilorasertib (ABT-348) is a potent and ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A with IC50s of 1 nM, 7 nM, 120 nM, respectively.

Availability: In stock

Package Price Qty
1 mg
$63.00
5 mg
$189.00
10 mg
$322.00
50 mg
$966.00
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Biological Activity

Ilorasertib (ABT-348) is a potent and ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A with IC50s of 1 nM, 7 nM, 120 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.47 mL 102.35 mL 204.69 mL
0.5 mM 4.09 mL 20.47 mL 40.94 mL
1 mM 2.05 mL 10.23 mL 20.47 mL
5 mM 0.41 mL 2.05 mL 4.09 mL

*The above data is based on the productmolecular weight 488.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20982
Actions Inhibitor
M. Wt 488.54
Formula C25H21FN6O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1227939-82-3
Synonyms ABT-348, ABT348, ABT 348
SMILES O=C(NC1=CC=CC(F)=C1)NC2=CC=C(C3=CSC4=C3C(N)=NC=C4C5=CN(CCO)N=C5)C=C2

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