Fig. 1 · Structure
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iMAC2 hydrochloride
MAC Inhibitor
iMAC2 hydrochloride is a potent inhibitor of the mitochondrial apoptosis-induced channel (MAC), displaying an IC50 of 28 nM. This compound effectively demonstrates anti-apoptotic activity by blocking the release of cytochrome c from mitochondria. iMAC2 hydrochloride is a valuable tool for studying apoptosis and its mechanisms in cellular models, making it suitable for researchers investigating mitochondrial function and associated pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 335166-00-2 |
| Applications | MAC Inhibitor |
| Formula | C19H22Br2Cl2FN3 |
| Molecular Weight | 542.11 |
| SMILES | FC(CN1CCNCC1)CN2C3=C(C4=C2C=CC(Br)=C4)C=C(Br)C=C3.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.