Fig. 1 · Structure
Documents & Downloads
Imatinib Acid
Imatinib Analogue
Imatinib Acid is an analogue of Imatinib, primarily targeting the Abelson tyrosine kinase (BCR-ABL) and other receptor tyrosine kinases. This compound exhibits potent inhibitory activity against cell proliferation and survival in various cancer cell lines, particularly those associated with chronic myeloid leukemia (CML). Imatinib Acid is a valuable tool for research into mechanisms of resistance to tyrosine kinase inhibitors and for developing new therapeutic strategies in oncology.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2741007-77-0 |
| Applications | Imatinib Analogue |
| Formula | C31H33N7O3 |
| Molecular Weight | 551.64 |
| SMILES | O=C(NC1=CC=C(C)C(NC2=NC(C3=CC=CN=C3)=CC=N2)=C1)C4=CC=C(CN5CCN(CCC(O)=O)CC5)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.